Silver and fluoride do different jobs
Silver can help a dentist tackle tooth decay through a professionally applied liquid treatment. The treatment is silver diamine fluoride, or SDF, a specially formulated dental solution containing silver and fluoride.
Silver acts against microbes, while fluoride helps minerals return to weakened tooth tissue, a process called remineralization. In suitable areas of decay, SDF can help arrest the disease: stop it progressing. That does not rebuild a missing part of a tooth or guarantee that a filling or other treatment will be unnecessary.
A lasting change in color
SDF can permanently turn the treated decayed tooth tissue dark or black. This irreversible staining needs to be discussed before treatment, particularly where it will be visible. The solution can also irritate the gums and other soft tissues.
A dentist must assess whether the treatment suits the tooth and the patient. Follow-up is important, and further applications may be needed. Darkening alone is not a reason to stop monitoring the tooth.
Professional care, with a specific purpose
In the United States, SDF has FDA clearance for treating tooth sensitivity. Using it to stop decay is off-label, meaning outside that cleared indication. For example, the 2023 clearance for Centrix FluoroSilver specifies sensitivity treatment in adults over 21; it is not clearance to treat every child’s cavity.
Professional guidance can address off-label uses. The American Academy of Pediatric Dentistry’s 2017 guideline conditionally recommends 38% SDF to stop decay in baby teeth where cavities have formed, based on low-quality evidence. Its current policy places SDF within an ongoing, individualized decay-management plan.
This is a professionally applied treatment, not a home remedy. Do not use homemade preparations or colloidal silver as substitutes, or delay dental assessment of a painful or damaged tooth.
About this edition
Original source and editorial notes
Adapted from original material by Rich Silver. Original source card: Silver fact: supplied original card (publication date not established).
Reviewed 2026-11-05. Replaced liquid-silver and guaranteed no-drilling language with selected-lesion caries arrest, limits, monitoring, and permanent staining. Silver diamine fluoride is retained as the common clinical spelling; diammine appears in some authoritative titles. Distinguished FDA-cleared hypersensitivity indications from off-label caries arrest, with a named FDA example and current professional guidance. No personal treatment advice, application dose or schedule, source graphic, card publication date, or unverified card URL is supplied. Reader-first revision: Leads with the professional silver/fluoride roles, defines arrest and remineralization, and keeps irreversible treated-decay staining visible. Preserves off-label versus cleared sensitivity indication, named adult-product example, qualified pediatric guideline, follow-up and non-home-use boundaries. The 2017 guideline scope is specifically cavitated lesions in baby teeth using the 38% formulation. No dose, application schedule, universal efficacy/safety or guaranteed no-drilling promise.
Sources & further reading
- American Dental Association: Silver Diamine Fluoride, clearance, off-label use, evidence, and adverse effects ↗
- FDA: Centrix FluoroSilver Silver Diamine Fluoride 38%, K222459 clearance and adult hypersensitivity indication (2023) ↗
- AAPD: Policy on the Use of Silver Diammine Fluoride for Pediatric Dental Patients, 2026 Reference Manual; latest policy revision 2023 ↗